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Idiopathic Parkinson's disease combined with multiple system atrophy. A clinicopathological report
Author(s) -
Hughes Andrew J.,
Daniel Susan E.,
Lees Andrew J.
Publication year - 1991
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.870060413
Subject(s) - olivopontocerebellar atrophy , atrophy , degenerative disease , pathology , pathological , lewy body , disease , central nervous system disease , parkinsonism , medicine , parkinson's disease , surgery
The clinical and postmortem findings of a patient with Lewy body pathology combined with multiple‐system atrophy are described. When alive the patient was diagnosed as having Parkinson's disease. Pathological examination found evidence of striatonigral and olivopontocerebellar degeneration, together with Lewy bodies at a number of sites characteristic for idiopathic Parkinson's disease. Taken together, the clinical history and histological findings support the coexistence of two disease processes.