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Domperidone‐induced acute dystonia and polycystic ovary syndrome
Author(s) -
Bonuccelli Ubaldo,
Nocchiero Aldo,
Napolitano Alessandro,
Paoletti Anna Maria,
Melis Gian Benedetto,
Corsini Giovanni Umberto,
Muratorio Alberto
Publication year - 1991
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.870060116
Subject(s) - polycystic ovary , domperidone , dystonia , medicine , ovary , endocrinology , psychiatry , dopamine , insulin , insulin resistance
The occurrence of acute dystonic reactions (ADRs) due to domperidone administration in two young women is reported. In both patients, a typical polycystic ovary (PCO) syndrome was found. The possibility that the relative hyperestrogenism typical of PCO syndrome acted as a facilitating factor for ADR is discussed.