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Parkinsonism secondary to bilateral striatal fungal abscesses
Author(s) -
Adler Charles H.,
Stem Matthew B.,
Brooks Tmichael L.
Publication year - 1989
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.870040407
Subject(s) - parkinsonism , mucormycosis , amphotericin b , stereotactic biopsy , medicine , fungal disease , pathology , brain biopsy , mycosis , aspergillosis , mptp , disease , biopsy , surgery , parkinson's disease , dermatology , immunology , antifungal
A 24‐year‐old man with an 11‐year history of i.v. drug use rapidly developed parkinsonism clinically indistinguishable from MPTP toxicity and Parkinson's disease. Although tests were negative for the human immunodeficiency virus, radiologic evaluation revealed bilateral striatal lesions. Stereotactic biopsy demonstrated septate hyphae consistent with either aspergillosis or mucormycosis. Gradual improvement followed systemic therapy with amphotericin B.