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Tics in a patient with Parkinson's disease
Author(s) -
Shale Heidi,
Fahn Stanley,
Mayeux Richard
Publication year - 1986
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.870010111
Subject(s) - tics , tourette syndrome , degenerative disease , parkinson's disease , levodopa , central nervous system disease , psychology , neurological disorder , medicine , disease , psychiatry , pediatrics , neuroscience
Abstract A patient with Gilles de la Tourette syndrome later developed Parkinson's disease in middle age. This was accompanied by a marked reduction in the frequency of tics but levodopa toxicity exacerbated the tics. The dopamine hypothesis of tic disorders is supported by this observation.