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Management of sleep disorders in Parkinson's disease and multiple system atrophy
Author(s) -
Videnovic Aleksandar
Publication year - 2017
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.26918
Subject(s) - alertness , parkinson's disease , atrophy , movement disorders , disease , medicine , sleep (system call) , neuroscience , psychology , rem sleep behavior disorder , psychiatry , physical medicine and rehabilitation , pathology , computer science , operating system
Parkinson's disease (PD) and multiple system atrophy (MSA) are disorders associated with α synuclein‐related neurodegeneration. Nonmotor symptoms are common hallmarks of these disorders, and disturbances of the sleep–wake cycle are among the most common nonmotor symptoms. It is only recently that sleep disturbances have received the attention of the medical and research community. Significant progress has been made in understanding the pathophysiology of sleep and wake disruption in alphasynucleinopathies during the past few decades. Despite these advancements, treatment options are limited and frequently associated with problematic side effects. Further studies that center on the development of novel treatment approaches are very much needed. In this article, the author discusses the current state of the management of disturbed sleep and alertness in PD and MSA. © 2017 International Parkinson and Movement Disorder Society