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Psychiatric and social outcome after deep brain stimulation for advanced Parkinson's disease
Author(s) -
Boel Judith A.,
Odekerken Vincent J.J.,
Geurtsen Gert J.,
Schmand Ben A.,
Cath Danielle C.,
Figee Martijn,
van den Munckhof Pepijn,
de Haan Rob J.,
Schuurman P. Richard,
de Bie Rob M.A.
Publication year - 2016
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.26468
Subject(s) - deep brain stimulation , subthalamic nucleus , parkinson's disease , psychiatry , psychology , medicine , disease
Background The aim of this study was to assess psychiatric and social outcome 12 months after bilateral deep brain stimulation (DBS) of the globus pallidus pars interna (GPi) and subthalamic nucleus (STN) for advanced Parkinson's disease (PD). Methods We randomly assigned patients to receive GPi DBS (n = 65) or STN DBS (n = 63). Standardized psychiatric and social questionnaires were assessed at baseline and after 12 months. Results No differences were found between GPi DBS and STN DBS on psychiatric evaluation. Within‐group comparisons showed small but statistically significant changes on several measures in both groups. Descriptive statistics indicated slight changes in social functioning. Marital satisfaction of patients and partners remained relatively stable after GPi and STN DBS. Conclusions We found neither differences in psychiatric and social outcome between GPi DBS and STN DBS nor any relevant within‐group differences. The decision for GPi DBS or STN DBS cannot be based on expected psychiatric or social effects. © 2015 International Parkinson and Movement Disorder Society