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Adaptive deep brain stimulation in a freely moving parkinsonian patient
Author(s) -
Rosa Manuela,
Arlotti Mattia,
Ardolino Gianluca,
Cogiamanian Filippo,
Marceglia Sara,
Di Fonzo Alessio,
Cortese Francesca,
Rampini Paolo M.,
Priori Alberto
Publication year - 2015
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.26241
Subject(s) - deep brain stimulation , neuroscience , stimulation , physical medicine and rehabilitation , essential tremor , parkinson's disease , brain stimulation , medicine , psychology , disease
The future of deep brain stimulation (DBS) for Parkinsonu0027s disease (PD) lies in new closed‐loop systems that continuously supply the implanted stimulator with new settings obtained by analyzing a feedback signal related to the patientu0027s current clinical condition.1 The most suitable feedback for PD is subthalamic local field potential (LFP) activity recorded from the stimulating electrode itself.2, 3, 4 This closed‐loop technology known as adaptive DBS (aDBS) recently proved superior to conventional open‐loop DBS (cDBS) in patients with PD.2