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Lower urinary tract function in dementia with Lewy bodies (DLB)
Author(s) -
Tateno Fuyuki,
Sakakibara Ryuji,
Ogata Tsuyoshi,
Kishi Masahiko,
Tsuyusaki Yohei,
Takahashi Osamu,
Sugiyama Megumi,
Tateno Akihiko
Publication year - 2015
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.25985
Subject(s) - dementia with lewy bodies , dementia , medicine , cystometry , urinary incontinence , parkinson's disease , urinary system , pure autonomic failure , urology , disease , orthostatic vital signs , blood pressure
Abstract Objectives Dementia with Lewy bodies (DLB) is the second most common degenerative cause of dementia, whereas lower urinary tract (LUT) function in DLB patients has not been fully delineated. We investigated LUT function in DLB by clinical‐urodynamic observations. Methods We examined 32 patients with DLB (23 men, 9 women; aged 59‐86 [mean, 75.9] years; disease duration, 0.2‐17 [3.3] years). All patients underwent an electromyography‐cystometry, and 21 patients underwent the sphincter motor unit potential analysis. Results Ninety‐one percent of patients had LUT symptoms: nighttime frequency (>8 times), 84%, and urinary incontinence (>1 per week), 50%. Detrusor overactivity was revealed in 87.1%, whereas postvoid residual was minimal. Neurogenic changes were shown in 50%. Conclusion LUT dysfunction is a common feature in DLB, attributable not only to dementia and immobility, but also to central and peripheral types of somato‐autonomic dysfunction. © 2014 International Parkinson and Movement Disorder Society