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Impaired self‐awareness of motor deficits in Parkinson's disease: Association with motor asymmetry and motor phenotypes
Author(s) -
Maier Franziska,
Prigatano George P.,
Kalbe Elke,
Barbe Michael T.,
Eggers Carsten,
Lewis Catharine J.,
Burns Richard S.,
MorroneStrupinsky Jeannine,
MoguelCobos Guillermo,
Fink Gereon R.,
Timmermann Lars
Publication year - 2012
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.25079
Subject(s) - psychology , postural instability , neuropsychology , parkinson's disease , gait , physical medicine and rehabilitation , disease , movement disorders , motor impairment , motor dysfunction , audiology , medicine , cognition , psychiatry
Background: This study investigated impaired self‐awareness of motor deficits in nondemented, nondepressed Parkinson's disease (PD) patients during a defined clinical on state. Methods: Twenty‐eight PD patients were examined. Patients' self‐ratings and experts' ratings of patients' motor performance were compared. Patient–examiner discrepancies and level of impairment determined severity of impaired self‐awareness. Motor exam assessed overall motor functioning, hemibody impairment, and 4 motor phenotypes. Neuropsychological tests were also conducted. Results: Signs of impaired self‐awareness were present in 17 patients (60.7%). Higher severity of impaired self‐awareness correlated significantly with higher postural‐instability and gait‐difficulty off scores ( r = .575; P = .001), overall motor off scores ( r = .569; P = .002), and higher left hemibody off scores ( r = .490; P = .008). In multiple linear regression analyses, higher postural‐instability and gait‐difficulty off scores remained as the only significant predictor of impaired self‐awareness severity. Conclusions: Postural instability and gait difficulties, disease severity, and right hemisphere dysfunction seem to contribute to impaired self‐awareness. © 2012 Movement Disorder Society