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A single‐question screen for rapid eye movement sleep behavior disorder: A multicenter validation study
Author(s) -
Postuma Ronald B.,
Arnulf Isabelle,
Hogl Birgit,
Iranzo Alex,
Miyamoto Tomoyuki,
Dauvilliers Yves,
Oertel Wolfgang,
Ju YoEl,
Puligheddu Monica,
Jennum Poul,
Pelletier Amelie,
Wolfson Christina,
LeuSemenescu Smaranda,
Frauscher Birgit,
Miyamoto Masayuki,
Cochen De Cock Valerie,
Unger Marcus M.,
StiasnyKolster Karin,
Livia Fantini Maria,
Montplaisir Jacques Y.
Publication year - 2012
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.25037
Subject(s) - parasomnia , rem sleep behavior disorder , gold standard (test) , rapid eye movement sleep , polysomnogram , medicine , medical diagnosis , sleep disorder , dementia , disease , psychology , psychiatry , parkinson's disease , polysomnography , electroencephalography , pathology , cognition
Background: Idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia that is an important risk factor for Parkinson's disease (PD) and Lewy body dementia. Its prevalence is unknown. One barrier to determining prevalence is that current screening tools are too long for large‐scale epidemiologic surveys. Therefore, we designed the REM Sleep Behavior Disorder Single‐Question Screen (RBD1Q), a screening question for dream enactment with a simple yes/no response. Methods: Four hundred and eighty‐four sleep‐clinic–based participants (242 idiopathic RBD patients and 242 controls) completed the screen during a multicenter case‐control study. All participants underwent a polysomnogram to define gold‐standard diagnosis according to standard criteria. Results: We found a sensitivity of 93.8% and a specificity of 87.2%. Sensitivity and specificity were similar in healthy volunteers, compared to controls or patients with other sleep diagnoses. Conclusions: A single‐question screen for RBD may reliably detect disease, with psychometric properties favorably comparable to those reported for longer questionnaires. © 2012 Movement Disorder Society