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The modified bradykinesia rating scale for Parkinson's disease: Reliability and comparison with kinematic measures
Author(s) -
Heldman Dustin A.,
Giuffrida Joseph P.,
Chen Robert,
Payne Megan,
Mazzella Filomena,
Duker Andrew P.,
Sahay Alok,
Kim Sang Jin,
Revilla Fredy J.,
Espay Alberto J.
Publication year - 2011
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.23740
Subject(s) - rating scale , physical medicine and rehabilitation , parkinson's disease , kinematics , psychology , intra rater reliability , reliability (semiconductor) , movement disorders , rhythm , inter rater reliability , finger tapping , physical therapy , disease , medicine , audiology , developmental psychology , physics , power (physics) , pathology , classical mechanics , quantum mechanics
Bradykinesia encompasses slowness, decreased movement amplitude, and dysrhythmia. Unified Parkinson's Disease Rating Scale–based bradykinesia‐related items require that clinicians condense abnormalities in speed, amplitude, fatiguing, hesitations, and arrests into a single score. The objective of this study was to evaluate the reliability of a modified bradykinesia rating scale, which separately assesses speed, amplitude, and rhythm and its correlation with kinematic measures from motion sensors. Fifty patients with Parkinson's disease performed Unified Parkinson's Disease Rating Scale–directed finger tapping, hand grasping, and pronation–supination while wearing motion sensors. Videos were rated blindly and independently by 4 clinicians. The modified bradykinesia rating scale and Unified Parkinson's Disease Rating Scale demonstrated similar inter‐ and intrarater reliability. Raters placed greater weight on amplitude than on speed or rhythm when assigning a Unified Parkinson's Disease Rating Scale score. Modified bradykinesia rating scale scores for speed, amplitude, and rhythm correlated highly with quantitative kinematic variables. The modified bradykinesia rating scale separately captures bradykinesia components with interrater and intrarater reliability similar to that of the Unified Parkinson's Disease Rating Scale. Kinematic sensors can accurately quantify speed, amplitude, and rhythm to aid in the development and evaluation of novel therapies in Parkinson's disease. © 2011 Movement Disorder Society