Premium
Subthreshold depression in Parkinson's disease
Author(s) -
Reiff Julia,
Schmidt Nele,
Riebe Bastian,
Breternitz Robert,
Aldenhoff Josef,
Deuschl Günther,
Witt Karsten
Publication year - 2011
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.23699
Subject(s) - parkinson's disease , depression (economics) , subthreshold conduction , medicine , physical medicine and rehabilitation , degenerative disease , psychology , psychiatry , neuroscience , central nervous system disease , disease , physics , transistor , quantum mechanics , voltage , economics , macroeconomics
Background: Quality of life in Parkinson patients with subthreshold depression could be improved if the prevalence and symptom profile were better understood. Methods: Our study used standard DSM‐IV and Judd criteria as well as motor, depression, and quality‐of‐life scales to investigate a sample of 110 nondemented Parkinson patients. This led to formation of nondepressed (48.2%), subthreshold depressed (25.5%), and depressed (26.4%) groups. Results: Quality of life was seen to be significantly lower in subthreshold depressed patients than in the nondepressed, and there were differences in the frequency of depressive symptoms that partially overlapped with nonmotor symptoms of vegetative origin in Parkinson's disease (appetite, sleep disorders). Key measures of depression (diminished interest/pleasure) were more frequent in the depressed group compared with the subthreshold depressed, although the motor functions of these 2 groups did not differ significantly. Conclusions: The Beck Depression Inventory score ranging from 9 to 15 points differentiates subthreshold depressed from nondepressed and depressed patients best. © 2011 Movement Disorder Society