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Subacute axonal neuropathy in Parkinson's disease with cobalamin and vitamin B6 deficiency under duodopa therapy
Author(s) -
Urban Peter P.,
Wellach Ingmar,
Faiss Siegbert,
Layer Peter,
Rosenkranz Thorsten,
Knop Karl,
Weis Joachim
Publication year - 2010
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.23342
Subject(s) - cobalamin , medicine , peripheral neuropathy , vitamin b6 , vitamin e deficiency , disease , neurology , nerve biopsy , pathology , gastroenterology , vitamin , vitamin b12 , vitamin e , endocrinology , biology , biochemistry , antioxidant , psychiatry , diabetes mellitus
We describe two patients who developed subacute axonal peripheral neuropathy under duodopa treatment. Comprehensive diagnostic workup including muscle and sural nerve biopsy revealed that the most probable cause of subacute axonal peripheral neuropathy was cobalaminand vitamin B6 deficiency in both the patients. © 2010 Movement Disorder Society