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Sensory alien hand syndrome in corticobasal degeneration: A cerebral blood flow study
Author(s) -
Delrieu Julien,
Payoux Pierre,
Toulza Olivier,
Esquerre JeanPaul,
Vellas Bruno,
Voisin Thierry
Publication year - 2010
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.23064
Subject(s) - corticobasal degeneration , cerebral blood flow , thalamus , medicine , sensory system , neuroscience , movement disorders , dementia , psychology , physical medicine and rehabilitation , anesthesia , pathology , disease
The presence of alien hand syndrome (AHS) is suggestive of the diagnosis of corticobasal degeneration when it develops in a progressive way. Sensory AHS (sAHS) should be distinguished from the motor form described more commonly. The physiopathology of sAHS remains unclear. The aim of this study is to determine cerebral regions involved in sAHS. We compared perfusion single photon emission computer tomography scans of patients with sAHS (n = 3) and without (n = 4). We observed significant decrease of regional cerebral blood flow over the nondominant thalamus in sAHS+ compared to sAHS− patients. This result suggests the involvement of the nondominant thalamus in sAHS. © 2010 Movement Disorder Society