Premium
Fatigue in Japanese patients with Parkinson's disease: A study using Parkinson fatigue scale
Author(s) -
Okuma Yasuyuki,
Kamei Satoshi,
Morita Akihiko,
Yoshii Fumihito,
Yamamoto Toshimasa,
Hashimoto Shiori,
Utsumi Hiroya,
Hatano Taku,
Hattori Nobutaka,
Matsumura Miyuki,
Takahashi Kazushi,
Nogawa Shigeru,
Watanabe Yuka,
Miyamoto Tomoyuki,
Miyamoto Masayuki,
Hirata Koichi
Publication year - 2009
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.22731
Subject(s) - parkinson's disease , rating scale , depression (economics) , quality of life (healthcare) , medicine , sleep disorder , logistic regression , physical therapy , cross sectional study , disease , psychology , psychiatry , insomnia , pathology , developmental psychology , nursing , economics , macroeconomics
The objective of this multicenter cross‐sectional study was to determine the prevalence of fatigue and factors contributing to it in a large sample of Japanese patients with Parkinson's disease (PD). We used the 16‐item Parkinson Fatigue Scale (PFS‐16), which was designed to assess fatigue exclusively associated with PD. We carried out this study using PFS‐16, the Unified Parkinson's Disease Rating Scale, Zung's Self‐Rating Depression Scale, Parkinson's Disease Sleep Scale (PDSS), and the PD quality of life (QOL) scale (PDQ‐39) by interview using questionnaires and physical examination by neurologists in 361 nondemented PD patients. Fatigue (an average PFS score of 3.3 or greater) was revealed in 151 patients (41.8%). Multiple logistic regression analysis indicated that the significant independent variables related to the presence of fatigue were the scores of PDSS and PDQ‐39. Depression score was not a significant contributing factor. Our study revealed that the prevalence of fatigue in Japanese PD patients is as high as that in Western countries, and that fatigue is a relatively independent symptom, although sleep disturbance may be associated with fatigue. Since fatigue is significantly related to QOL reduction, therapeutic interventions including treatment of sleep disturbance are important. © 2009 Movement Disorder Society