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Pain in Parkinson's disease
Author(s) -
Ford Blair
Publication year - 2010
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.22716
Subject(s) - neuropathic pain , parkinson's disease , disease , medicine , dystonia , motor symptoms , physical medicine and rehabilitation , degenerative disease , neurological disorder , complex regional pain syndrome , physical therapy , psychology , central nervous system disease , psychiatry , anesthesia , surgery , pathology
Parkinson's disease is characterized primarily as a neurodegenerative disorder that leads to disabling motor and cognitive impairment. PD is less widely appreciated as a disease causing a substantial variety of pain syndromes, although the prevalence of pain in PD is approximately 40%. In a minority of patients, pain is so severe and intractable that it overshadows the motor symptoms of the disorder. In recent years, descriptive surveys of non‐motor symptoms in PD have led to a classification of painful sensations into one or more of several categories: musculoskeletal pain, radicular or neuropathic pain, dystonia‐related pain, akathitic discomfort, and primary, central parkinsonian pain. A framework for diagnosing and treating painful PD is described in this review, together with recent insignts into the neurophysiological mechanisms and substrates of pain in PD. © 2010 Movement Disorder Society