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Bilateral deep brain stimulation of the globus pallidus internus in tardive dystonia
Author(s) -
Sako Wataru,
Goto Satoshi,
Shimazu Hideki,
Murase Nagako,
Matsuzaki Kazuhito,
Tamura Tetsuya,
Mure Hideo,
Tomogane Yusuke,
Arita Norio,
Yoshikawa Hiroo,
Nagahiro Shinji,
Kaji Ryuji
Publication year - 2008
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.22100
Subject(s) - deep brain stimulation , dystonia , refractory (planetary science) , movement disorders , globus pallidus , tardive dyskinesia , medicine , neurological disorder , psychology , anesthesia , physical medicine and rehabilitation , neuroscience , central nervous system disease , surgery , basal ganglia , psychiatry , parkinson's disease , schizophrenia (object oriented programming) , central nervous system , disease , physics , astrobiology
Tardive dystonia is a disabling movement disorder as a consequence of exposure to neuroleptic drugs. We followed 6 patients with medically refractory tardive dystonia treated by bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) for 21 ± 18 months. At last follow‐up, the Burke‐Fahn‐Marsden Dystonia Rating Scale (BFMDRS) motor score improved by 86% ± 14%, and the BFMDRS disability score improved by 80% ± 12%. Bilateral GPi‐DBS is a beneficial therapeutic option for the long‐term relief of tardive dystonia. © 2008 Movement Disorder Society