Regression of symptoms after selective iron chelation therapy in a case of neurodegeneration with brain iron accumulation | Zendy

Forni Gian Luca | Zendy; Balocco Manuela | Zendy; Cremonesi Laura | Zendy; Abbruzzese Giovanni | Zendy; Parodi Roberto Carlo | Zendy; Marchese Roberta | Zendy

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Regression of symptoms after selective iron chelation therapy in a case of neurodegeneration with brain iron accumulation

Author(s) -

Forni Gian Luca,

Balocco Manuela,

Cremonesi Laura,

Abbruzzese Giovanni,

Parodi Roberto Carlo,

Marchese Roberta

Publication year - 2008

Publication title -

movement disorders

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.352

H-Index - 198

eISSN - 1531-8257

pISSN - 0885-3185

DOI - 10.1002/mds.22002

Subject(s) - chelation therapy , neurodegeneration , chelation , medicine , neuroscience , psychology , chemistry , disease , organic chemistry

We report the results of iron chelating treatment with deferiprone in a 61‐year‐old woman with signs and symptoms of neurodegeneration with brain iron accumulation (NBIA). After 6 months of therapy the patient's gait had improved and a reduction in the incidence of choreic dyskinesias was observed. Her gait returned to normal after an additional 2 months of therapy, at which time there was a further reduction in involuntary movements and a partial resolution of the blepharospasm. © 2008 Movement Disorder Society

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