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Clinical and neurophysiological characterization of myoclonus in complex regional pain syndrome
Author(s) -
Munts Alexander G.,
Van Rootselaar AnneFleur,
Van Der Meer Johan N.,
Koelman Johannes H.T.M.,
Van Hilten Jacobus J.,
Tijssen Marina A.J.
Publication year - 2007
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.21910
Subject(s) - myoclonus , electromyography , dystonia , complex regional pain syndrome , physical medicine and rehabilitation , psychology , coherence (philosophical gambling strategy) , neurophysiology , neurological disorder , medicine , anesthesia , neuroscience , central nervous system disease , physics , quantum mechanics
The origin of myoclonus in patients with complex regional pain syndrome (CRPS) is unknown. Eight patients with CRPS related myoclonus were clinically evaluated and studied with intermuscular and corticomuscular coherence analysis. Jerks were present at rest, aggravated during action and were frequently associated with tremulousness or dystonia. Electromyography demonstrated a burst duration ranging from 25 to 240 ms with burst frequencies varying from <1 jerk/s during rest to 20 Hz during action. Coherence studies showed increased intermuscular coherence in 4 patients in the 6 to 12 Hz band, as reported in patients with enhanced physiological tremor. In 2 patients side‐to‐side coherence was observed, pointing to a central oscillatory drive. Significant coherence entrainment was detected in 5 patients. We conclude that the characteristics of myoclonus in CRPS are different from other forms of myoclonus. © 2007 Movement Disorder Society