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Carotid intima‐media thickness in Parkinson's disease
Author(s) -
Lee JongMoon,
Park KunWoo,
Seo WooKeun,
Park Moon Ho,
Han Changsu,
Jo Inho,
Ahn Jo Sangmee
Publication year - 2007
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.21757
Subject(s) - medicine , intima media thickness , cardiology , subclinical infection , parkinson's disease , tunica media , disease , central nervous system disease , vascular disease , carotid arteries
There have been a few studies and inconsistent results regarding the coincidence of Parkinson's disease (PD) and atherosclerotic diseases, such as cerebrovascular disease. Carotid intima‐media thickness (IMT) is a known marker for subclinical atherosclerosis. The aim of this study was to investigate the carotid IMT between PD patients and controls. We studied 43 patients with PD and 86 matched controls. The carotid IMT in PD patients was significantly smaller than in controls (0.796 ± 0.179 mm vs. 0.913 ± 0.237 mm, P < 0.05). In multivariate analysis, the carotid IMT was inversely associated with the duration of levodopa medication and the severity of PD. These results suggest that PD patients have a lower risk of atherosclerosis. © 2007 Movement Disorder Society