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Deep brain stimulation in Tourette's syndrome
Author(s) -
Bajwa Rizma Jalees,
de Lotbinière Alain J.,
King Robert A.,
Jabbari Bahman,
Quatrano Susan,
Kunze Kimberly,
Scahill Lawrence,
Leckman James F.
Publication year - 2007
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.21398
Subject(s) - deep brain stimulation , tics , tourette syndrome , thalamus , psychology , weakness , neurological disorder , subthalamic nucleus , medicine , central nervous system disease , neuroscience , physical medicine and rehabilitation , surgery , psychiatry , parkinson's disease , disease
Abstract A 48‐year‐old man with severe, lifelong Tourette's syndrome (TS) characterized by forceful self‐injurious motor tics and obsessive‐compulsive disorder was treated with bilateral deep brain stimulation (DBS). The decision to treat was based on his progressive neurological impairment (left sided weakness secondary to spinal cord injury) because of his relentless, violent head jerks. Electrodes were implanted at the level of the medial part of the thalamus (centromedian nucleus, the substantia periventricularis, and the nucleus ventro‐oralis internus). DBS resulted in a substantial reduction of tics. These data show that bilateral DBS of the thalamus can have a good effect on severe tics in adult patients suffering from intractable TS. © 2007 Movement Disorder Society

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