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Simple clinical tests may predict severe oropharyngeal dysphagia in Parkinson's disease
Author(s) -
Lam Kuen,
Kwai Yi Lam Florence,
Kwong Lau Kwok,
Kay Chan Yiu,
Yee Ling Kan Elaine,
Woo Jean,
Kee Wong Fat,
Ko Andrew
Publication year - 2007
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.21362
Subject(s) - dysphagia , parkinson's disease , oropharyngeal dysphagia , medicine , disease , physical medicine and rehabilitation , surgery
Objective: To determine if simple screening tests can predict severe oropharyngeal dysphagia in subjects with Parkinson's disease. Methodology: Forty‐five subjects (26 females) of average age 75 (range: 65–94) who were classified as Modified Hoehn and Yahr stages 2 to 5 were enrolled. The presence of oropharyngeal dysphagia was assessed by a symptom questionnaire, 50 ml water swallowing test and videofluroscopic swallowing study. Results: Six of the subjects had severe oropharyngeal dysphagia in videofluroscopic swallowing study. Subsequent multivariate analysis showed that 3 factors could independently predict severe oropharyngeal dysphagia. These included higher Modified Hoehn and Yahr stage ( P = 0.042), low Body mass index ( P = 0.014), and increased difficulty in keeping food or drink in the mouth ( P = 0.047). The regression model had a positive predictive power of 96% (sensitivity: 83.3%, specificity: 97.4%). Conclusion: A combination of 3 simple clinical parameters may be useful for screening for severe oropharyngeal dysphagia as shown radiologically in subjects with Parkinson's disease. © 2007 Movement Disorder Society