Premium
Deep brain stimulation: Neuropsychological and neuropsychiatric issues
Author(s) -
Voon Valerie,
Kubu Cynthia,
Krack Paul,
Houeto JeanLuc,
Tröster Alexander I.
Publication year - 2006
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.20963
Subject(s) - deep brain stimulation , neuropsychology , cognition , parkinson's disease , movement disorders , physical medicine and rehabilitation , motor symptoms , psychology , neuropsychiatry , medicine , psychiatry , neuroscience , disease , neuroimaging
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor, cognitive, neuropsychiatric, autonomic, and other nonmotor symptoms. The efficacy of deep brain stimulation (DBS) for the motor symptoms of advanced PD is well established. However, the effects of DBS on the cognitive and neuropsychiatric symptoms are less clear. The neuropsychiatric aspects of DBS for PD have recently been of considerable clinical and pathophysiological interest. As a companion to the preoperative and postoperative sections of the DBS consensus articles, this article reviews the published literature on the cognitive and neuropsychiatric aspects of DBS for PD. The majority of the observed neuropsychiatric symptoms are transient, treatable, and potentially preventable. Outcome studies, methodological issues, pathophysiology, and preoperative and postoperative management of the cognitive and neuropsychiatric aspects and complications of DBS for PD are discussed. © 2006 Movement Disorder Society