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Online movement control in multiple sclerosis patients with tremor: Effects of tendon vibration
Author(s) -
Feys Peter,
Helsen Werner F.,
Verschueren Sabine,
Swinnen Stephan P.,
Klok Isabel,
Lavrysen Ann,
Nuttin Bart,
Ketelaer Pierre,
Liu Xuguang
Publication year - 2006
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.20938
Subject(s) - proprioception , physical medicine and rehabilitation , multiple sclerosis , wrist , medicine , afferent , motor control , psychology , audiology , neuroscience , surgery , psychiatry
Patients with intention tremor due to multiple sclerosis (MS) exhibit an increased reliance on visual feedback in the sensorimotor control of slow goal‐directed movements. In the present study, the use of proprioceptive information was investigated in MS patients with intention tremor compared to MS patients without tremor and healthy controls. Tendon vibration was applied to the wrist extensor muscles during a memory‐guided slow wrist step‐tracking task to investigate the use of muscle spindle afferent information in online movement control. A significant reduction of movement amplitude was induced by tendon vibration in all three groups, but the effect was found to be smaller in MS patients with tremor (28%) than in subjects without tremor (50%). Vibration also induced an increase of overall tremor amplitude in the MS tremor group; however, its effect on movement amplitude was not directly related to (changes in) tremor severity. The results suggest that the decreased online use of proprioceptive information in MS patients with tremor reflects an adaptation over time to cope with a tremor‐related noisy background. Abnormalities in proprioceptive processing may explain why MS patients with tremor show an increased reliance on visual feedback for online motor control. © 2006 Movement Disorder Society