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Cardiac 123 I‐MIBG scintigraphy in patients with essential tremor
Author(s) -
Lee Phil Hyu,
Kim Ji Won,
Bang Oh Young,
Joo In Soo,
Yoon SeokNam,
Huh Kyoon
Publication year - 2006
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.20908
Subject(s) - essential tremor , medicine , parkinson's disease , scintigraphy , mediastinum , nuclear medicine , cardiology , central nervous system disease , radiology , disease , physical medicine and rehabilitation
In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using 123 I‐metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor‐dominant PD (TDPD). The mean ratio of 123 I‐MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD. © 2006 Movement Disorder Society