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Camptocormia associated with focal myositis in multiple‐system atrophy
Author(s) -
Diederich Nico J.,
Goebel Hans H.,
Dooms Georges,
Bumb Anja,
Huber Frank,
Kompoliti Katie,
Meinck HansMichael M.
Publication year - 2006
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.20686
Subject(s) - medicine , atrophy , myositis , magnetic resonance imaging , hyperintensity , muscle biopsy , progressive muscular atrophy , trunk , pathology , biopsy , radiology , disease , amyotrophic lateral sclerosis , ecology , biology
Camptocormia (CC) or pronounced forward flexion of the trunk is a common symptom of Parkinson's disease. We describe 2 patients with probable, respectively possible multiple‐system atrophy and CC. Magnetic resonance imaging of the erector trunci showed focal patchy hyperintensities with gadolinium enhancement and muscle biopsy was indicative of variably pronounced focal myositis. CC was progressive and the major handicap for both patients after 1 and 1.5 years of follow‐up, respectively. The therapeutic response was poor. Similarities with the dropped‐head syndrome suggest that the muscle pathology may be either the primary cause of CC, a focal reaction to the CC posture, or a coincident syndrome of old age. © 2005 Movement Disorder Society