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Tegaserod (Zelnorm) for the treatment of constipation in Parkinson's disease
Author(s) -
Sullivan Kelly L.,
Staffetti Joseph F.,
Hauser Robert A.,
Dunne Peter B.,
Zesiewicz Theresa A.
Publication year - 2006
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.20666
Subject(s) - constipation , tegaserod , medicine , parkinson's disease , placebo , disease , defecation , physical therapy , alternative medicine , pathology
We performed a double‐blind randomized placebo‐controlled pilot study to determine the efficacy of tegaserod (Zelnorm) in treating constipation in 15 patients with Parkinson's disease (PD). There was a trend for improvement in the Subject's Global Assessment (SGA) of satisfaction with bowel habits (NS) and the total SGA (including abdominal discomfort, bothersome constipation, and satisfaction; NS). © 2005 Movement Disorder Society