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Corticospinal excitability during motor imagery of a simple tonic finger movement in patients with writer's cramp
Author(s) -
Quartarone Angelo,
Bagnato Sergio,
Rizzo Vincenzo,
Morgante Francesca,
Sant'Angelo Antonino,
Crupi Domenica,
Romano Marcello,
Messina Corrado,
Berardelli Alfredo,
Girlanda Paolo
Publication year - 2005
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.20626
Subject(s) - transcranial magnetic stimulation , motor imagery , tonic (physiology) , forearm , psychology , physical medicine and rehabilitation , index finger , hand muscles , motor cortex , neuroscience , evoked potential , electromyography , stimulation , medicine , electroencephalography , anatomy , brain–computer interface
Motor imagery (MI) is the mental rehearsal of a motor act without overt movement. Using transcranial magnetic stimulation (TMS), we tested the effect of MI on corticospinal excitability in patients with writer's cramp. In 10 patients with writer's cramp and 10 healthy controls, we applied focal TMS over each primary motor area and recorded motor evoked potentials (MEPs) from contralateral hand and arm muscles while participants imagined a tonic abduction of the index finger contralateral to the stimulated hemisphere. In healthy controls and patients, the MEP amplitude in the relaxed first dorsal interosseus muscle (FDI) showed a muscle‐specific increase during MI; however, the increase was less pronounced in patients than in healthy controls. In addition, in patients but not in controls, the MEP amplitude also increased in hand and forearm muscles not involved in the imagined movement. This abnormal spread of facilitation was observed in the affected and unaffected upper limb. MI of simple hand movements is less efficient and less focussed in patients with writer's cramp than it is in normal subjects. © 2005 Movement Disorder Society