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Efficient internal pallidal stimulation in Gilles de la Tourette syndrome: A case report
Author(s) -
Diederich Nico J.,
Kalteis Karin,
Stamenkovic Mara,
Pieri Vannina,
Alesch François
Publication year - 2005
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.20551
Subject(s) - deep brain stimulation , tics , tourette syndrome , globus pallidus , psychology , stimulation , tourette's syndrome , pallidotomy , thalamic stimulator , movement disorders , subthalamic nucleus , physical medicine and rehabilitation , medicine , neuroscience , basal ganglia , parkinson's disease , psychiatry , central nervous system , disease
Abstract The usefulness of deep brain stimulation (DBS) of thalamic nuclei in Gilles de la Tourette syndrome (GTS) has recently been advocated. We report on a 14‐month follow‐up study of a patient with intractable GTS in whom bilateral DBS of the internal globus pallidus was carried out. Tic frequency per minute decreased by 73% in the postoperative phase and in particular the vocal tics became less intense. Pronation/ supination bradykinesia of the left extremities was a well‐tolerated, permanent side effect. Pallidal DBS could become a valuable rescue therapy for otherwise intractable GTS. © 2005 Movement Disorder Society