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Sporadic rapid‐onset dystonia–parkinsonism syndrome: Failure of bilateral pallidal stimulation
Author(s) -
Deutschländer Angela,
Asmus Friedrich,
Gasser Thomas,
Steude Ulrich,
Bötzel Kai
Publication year - 2005
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.20296
Subject(s) - dystonia , parkinsonism , deep brain stimulation , levodopa , medicine , carbidopa , stimulation , globus pallidus , pallidotomy , age of onset , degenerative disease , pediatrics , central nervous system disease , anesthesia , psychology , surgery , basal ganglia , parkinson's disease , disease , psychiatry , central nervous system
We report on a woman who had a severe sporadic nonprogressive dystonia–parkinsonism syndrome with rapid onset of symptoms at age 21. Secondary causes for dystonia were ruled out. No response to levodopa/carbidopa was seen. The patient fulfilled all diagnostic criteria of rapid‐onset dystonia–parkinsonism, except for autosomal‐dominant inheritance. Bilateral deep brain stimulation of the globus pallidus failed to alleviate her symptoms. © 2004 Movement Disorder Society
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