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Improvement of blepharospasm with Zolpidem
Author(s) -
Garretto Nélida Susana,
Bueri José A.,
Rey Roberto D.,
Arakaki Tomoko,
Nano Gabriela V.,
Mancuso Marcela
Publication year - 2004
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.20085
Subject(s) - blepharospasm , zolpidem , basal ganglia , neuroscience , psychology , medicine , pharmacology , botulinum toxin , insomnia , central nervous system
Zolpidem (ZLP) is an imidazopyridine that binds to GABA receptors. We report on improvement of blepharospasm in 3 patients treated with ZLP. The GABAergic action of this drug on the output structures of the basal ganglia could explain the improvement of blepharospasm in these patients. © 2004 Movement Disorder Society