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Deep brain stimulation in myoclonus–dystonia syndrome
Author(s) -
Cif Laura,
Valente Enza Maria,
Hemm Simone,
Coubes Christine,
Vayssiere Nathalie,
Serrat Stéphanie,
Di Giorgio Annalisa,
Coubes Philippe
Publication year - 2004
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.20030
Subject(s) - dystonia , deep brain stimulation , myoclonus , neuroscience , stimulation , medicine , movement disorders , neurological disorder , essential tremor , physical medicine and rehabilitation , psychology , central nervous system disease , parkinson's disease , disease
Myoclonus–dystonia syndrome (MDS) is an autosomal dominant disorder characterized by bilateral myoclonic jerks. An 8‐year‐old boy presenting with early onset, medically intractable, MDS due to a mutation in the ϵ‐sarcoglycan gene (SGCE) underwent chronic bilateral stimulation of the globus pallidus internus, which eliminates both myoclonus and dystonia. We conclude that deep brain stimulation can be an effective and safe treatment for MDS. © 2004 Movement Disorder Society