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Stiff leg syndrome: Case report
Author(s) -
Gürol Mahmut Edip,
Ertas Mustafa,
Hanagasi Hasmet Ayhan,
Sahin Hüseyin Alparslan,
Gürsoy Gençay,
Emre Murat
Publication year - 2001
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.1224
Subject(s) - stiff person syndrome , clonazepam , medicine , lumbar , physical medicine and rehabilitation , psychology , surgery , anesthesia , glutamate decarboxylase , biochemistry , chemistry , enzyme
We report on a 28‐year‐old woman with insulin‐resistant diabetes mellitus with a 5‐year history of progressive stiffness and painful spasms of the right leg, exaggerated by sudden auditory and tactile stimuli or by emotional stress. There were no signs of truncal rigidity or exaggerated lumbar lordosis. Anti‐glutamic acid decarboxylase antibodies were positive in her serum. She improved substantially with clonazepam 4 mg/day. She presented with electrophysiological findings not previously reported in stiff leg syndrome, which may suggest increased inhibition in the uninvolved upper extremities. © 2001 Movement Disorder Society.