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Frontotemporal dementia and Parkinsonism linked to chromosome 17 (FTDP‐17): PPND family. A longitudinal videotape demonstration
Author(s) -
Wszolek Zbigniew K.,
Kardon Randy H.,
Wolters Erik Ch.,
Pfeiffer Ronald F.
Publication year - 2001
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.1131
Subject(s) - parkinsonism , frontotemporal dementia , dementia , psychology , neuroscience , corticobasal degeneration , degenerative disease , phenotype , pathology , medicine , central nervous system disease , biology , genetics , disease , gene
Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP‐17), characterized by an autosomal dominant inheritance pattern, has recently been recognized as a distinct entity that can display a confusingly broad clinical phenotype. The pallido‐ponto‐nigral degeneration (PPND) variant is the prototypical example of the parkinsonism‐predominant pattern of FTDP‐17. A longitudinal videotape demonstration of the clinical progression of this entity in a single individual, along with brief videotape segments from three additional affected individuals, is presented in order to facilitate recognition of this disorder. © 2001 Movement Disorder Society.