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Case report of pallido‐pyramidal disease with supplementary motor area involvement
Author(s) -
Pradat PierreFrançois,
DupelPottier Corinne,
Lacomblez Lucette,
Salachas François,
Meininger Vincent,
Lacomblez Lucette,
Spelle Laurent,
Bonnaud Isabelle,
Ribeiro Marie Joao,
Remy Philippe,
Samson Yves
Publication year - 2001
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.1126
Subject(s) - precentral gyrus , basal ganglia , flumazenil , motor cortex , supplementary motor area , frontal cortex , neuroscience , positron emission tomography , cortex (anatomy) , medicine , frontal lobe , degenerative disease , psychology , apraxia , central nervous system disease , magnetic resonance imaging , central nervous system , benzodiazepine , aphasia , radiology , receptor , functional magnetic resonance imaging , stimulation
An C‐flumazenil positron emission tomography (PET) study in a patient with pallido‐pyramidal disease revealed a marked decrease in benzodiazepine‐receptor density in the precentral gyrus cortex and the mesial frontal cortex. We suggest that, in addition to dysfunction of basal ganglia‐dependent systems, degeneration of the supplementary motor area could also be involved in the patient's bradykinesia. © 2001 Movement Disorder Society.