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Partial lesion of thalamic ventral intermediate nucleus after chronic high‐frequency stimulation
Author(s) -
Henderson Jasmine,
Rodriguez Michael,
O'Sullivan Dudley,
Pell Malcolm,
Fung Victor,
Benabid Alim Louis,
Halliday Glenda
Publication year - 2004
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.10709
Subject(s) - neuropathology , thalamic stimulator , stimulation , deep brain stimulation , thalamus , medicine , lesion , neuroscience , parkinson's disease , psychology , pathology , disease
Abstract A 73‐year‐old man with Parkinson's disease underwent thalamic stimulation for disabling tremor with excellent results only when stimulation on . Post‐mortem neuropathology (7 years postoperatively) revealed 60% cell loss within 0.5 mm of the electrode tip. Tremor improvement was attributable to chronic stimulation, not microthalamotomy. © 2004 Movement Disorder Society