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Spatial patterns of α‐synuclein positive glial cytoplasmic inclusions in multiple system atrophy
Author(s) -
Armstrong Richard A.,
Lantos Peter L.,
Cairns Nigel J.
Publication year - 2004
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.10637
Subject(s) - synucleinopathies , cytoplasmic inclusion , atrophy , alpha synuclein , pathology , cytoplasm , biology , neuroscience , parkinson's disease , medicine , microbiology and biotechnology , disease
In cases of multiple system atrophy (MSA), glial cytoplasmic inclusions (GCI) were distributed randomly or present in large diffuse clusters (>1,600 μm in diameter) in most areas studied. These spatial patterns contrast with those reported for filamentous neuronal inclusions in the tauopathies and α‐synucleinopathies. © 2003 Movement Disorder Society
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