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Efficacy of propranolol in hyperthyroid‐induced chorea: A case report
Author(s) -
Hayashi Ryoichi,
Hashimoto Takao,
Tako Kenji
Publication year - 2003
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.10477
Subject(s) - chorea , propranolol , choreiform movement , medicine , basal ganglia , movement disorders , basal (medicine) , pathogenesis , neurological disorder , endocrinology , pediatrics , dyskinesia , central nervous system disease , parkinson's disease , central nervous system , disease , insulin
We describe a thyrotoxic patient with choreic movements. The latter gradually receded and disappeared as the patient was treated with methimazole and β‐adrenoceptor blocker, and the improvement deteriorated during a β‐adrenoceptor challenge test. Our findings suggest that the pathogenesis of thyrotoxic chorea seems more likely to be of biochemical origin rather than due to structural changes in the basal ganglia. © 2003 Movement Disorder Society