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Tetrabenazine in the treatment of severe pediatric chorea
Author(s) -
Chatterjee Anjan,
Frucht Steven J.
Publication year - 2003
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.10427
Subject(s) - tetrabenazine , chorea , movement disorders , medicine , pediatrics , psychiatry , disease , dopamine
Tetrabenazine (TBZ) is widely used to treat adults with hyperkinetic movement disorders; however, published experience with the drug in pediatric patients is limited. We report on 5 children with severe chorea who were treated with TBZ. TBZ effectively controlled chorea in 4 patients, and despite the need for relatively high doses, it was well tolerated. © 2003 Movement Disorder Society