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Globus pallidus internus deep brain stimulation for dystonic conditions: A prospective audit
Author(s) -
Yianni John,
Bain Peter,
Giladi Nir,
Auca Marieta,
Gregory Ralph,
Joint Carole,
Nandi Dipankar,
Stein John,
Scott Richard,
Aziz Tipu
Publication year - 2003
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.10380
Subject(s) - deep brain stimulation , dystonia , spasmodic torticollis , medicine , globus pallidus , physical medicine and rehabilitation , movement disorders , cervical dystonia , stimulation , torticollis , pallidotomy , neurological disorder , psychology , neuroscience , central nervous system disease , surgery , basal ganglia , parkinson's disease , central nervous system , disease
In the current era of functional surgery for movement disorders, deep brain stimulation (DBS) of the globus pallidus internus (GPi) is emerging as the favoured target in the treatment of patients with dystonia. The results of 25 consecutive patients with medically intractable dystonia (12 with generalised dystonia, 7 with spasmodic torticollis, and 6 with other types of dystonia) treated with GPi stimulation are reported. Although comparisons were limited by differences in their respective neurological rating scales, chronic DBS benefited all groups, resulting in clear and progressive improvements in their condition. This study clearly demonstrates that DBS of the GPi provides amelioration of intractable dystonia. © 2002 Movement Disorder Society