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Secondary nonresponsiveness to new bulk botulinum toxin A (BCB2024)
Author(s) -
Racette Brad A.,
Stambuk Mikula,
Perlmutter Joel S.
Publication year - 2002
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.10209
Subject(s) - cervical dystonia , blepharospasm , botulinum toxin , toxin , medicine , dystonia , anesthesia , microbiology and biotechnology , biology , psychiatry
We report on a patient with cranio–cervical dystonia injected with the new, lower protein formulation of botulinum toxin A who developed secondary resistance to this toxin. Subsequent injections with botulinum toxin B provided substantial reduction of blepharospasm. This is the first reported case of secondary resistance to the new preparation of botulinum toxin A. © 2002 Movement Disorder Society