Association between dopamine transporter gene polymorphism and susceptibility to Parkinson's disease in Japan | Zendy

Nishimura Masataka | Zendy; Kaji Ryuji | Zendy; Ohta Mitsuhiro | Zendy; Mizuta Ikuko | Zendy; Kuno Sadako | Zendy

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Association between dopamine transporter gene polymorphism and susceptibility to Parkinson's disease in Japan

Author(s) -

Nishimura Masataka,

Kaji Ryuji,

Ohta Mitsuhiro,

Mizuta Ikuko,

Kuno Sadako

Publication year - 2002

Publication title -

movement disorders

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.352

H-Index - 198

eISSN - 1531-8257

pISSN - 0885-3185

DOI - 10.1002/mds.10187

Subject(s) - dopamine transporter , parkinson's disease , genotype , dopamine , polymorphism (computer science) , gene polymorphism , medicine , genetics , disease , degenerative disease , genetic predisposition , gene , biology , dopaminergic

We studied a polymorphism in the dopamine transporter (DAT) gene in 236 Japanese patients with Parkinson's disease (PD) and compared the results with 220 controls. The 1215A/G genotype of the DAT gene was significantly different between PD patients and controls, suggesting a possible involvement of DAT in genetic susceptibility to PD. © 2002 Movement Disorder Society

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