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Intraoperative micro‐ and macrostimulation of the subthalamic nucleus in Parkinson's disease
Author(s) -
Pollak Pierre,
Krack Paul,
Fraix Valérie,
Mendes Alexandre,
Moro Elena,
Chabardes Stephan,
Benabid AlimLouis
Publication year - 2002
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.10158
Subject(s) - subthalamic nucleus , stimulation , deep brain stimulation , parkinson's disease , neuroscience , rigidity (electromagnetism) , medicine , degenerative disease , central nervous system disease , physical medicine and rehabilitation , psychology , disease , physics , pathology , quantum mechanics
Abstract Studying the clinical effects induced by electrical stimulation of the subthalamic nucleus (STN) area in a parkinsonian patient under local anesthesia is a mandatory step to determine the precise location of the final chronic electrode. Using multiple microelectrodes, preferably in a concentric parallel array allows a precise mapping of the STN region. The most reliable features to determine the suitable target are stimulation‐induced dyskinesias and rigidity decrease at a low intensity without adverse effects or only at far higher intensities. New skills are needed to assess all stimulation‐induced effects and interpret them in anatomo‐functional terms. © 2002 Movement Disorder Society