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Microelectrode recordings in the pallidum
Author(s) -
Lozano Andres M.,
Hutchison William D.
Publication year - 2002
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.10157
Subject(s) - globus pallidus , internal capsule , neuroscience , dystonia , movement disorders , deep brain stimulation , medicine , subthalamic nucleus , local field potential , microelectrode , basal ganglia , psychology , parkinson's disease , pathology , disease , magnetic resonance imaging , central nervous system , radiology , chemistry , electrode , white matter
The internal segment of the globus pallidus (GPi) is being targeted in neurosurgical procedures to treat Parkinson's disease and dystonia. Precise targeting of the pallidal complex is important in determining the efficacy of the surgical intervention and for the avoidance of adverse effects. Intraoperative microelectrode recording can be used to characterize the patterns of activity and receptive field properties of single pallidal neurons and to identify important bordering structures, including the optic tract and internal capsule. Because the clinical features of movement disorders can be differentially affected as a function of location within the pallidal complex, further refinements in intraoperative targeting may become important. © 2002 Movement Disorder Society