Open AccessFacile synthesis of β‐cyclodextrin‐grafted solid silica nanoparticles
Author(s) -
Jadhav Sushilkumar A.,
Karande Sudip D.,
Burungale Shivaji H.
Publication year - 2019
Publication title -
material design & processing communications
Language(s) - English
Resource type - Journals
ISSN - 2577-6576
DOI - 10.1002/mdp2.75
Subject(s) - grafting , cyclodextrin , surface modification , imidazole , nanoparticle , chemistry , carbamate , polymer chemistry , condensation reaction , condensation , combinatorial chemistry , organic chemistry , materials science , catalysis , nanotechnology , polymer , physics , thermodynamics
In this work, a simple and reliable method for the synthesis of β‐cyclodextrin (β‐CD)–grafted silica nanoparticles (SiNPs) is developed. The synthetic protocol included postsynthesis functionalization of silica nanoparticles with aminopropyl trimethoxysilane (APTES) followed by the condensation of the amino groups with imidazole carbamate ester of β‐CD. The activated β‐CD (carbamate ester) was prepared by reacting it with carbonyldiimidazole (CDI). The grafting of (β‐CD) on SiNPs was confirmed by ATIR‐IR, DLS, and TGA analyses. The method developed can be easily reproduced with any other oxide nanoparticles for the preparation of β‐CD‐grafted nanoparticles.