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The Impact of Dietary Intake and Physical Activity on Body Composition in Parkinson's Disease
Author(s) -
Rivadeneyra Jessica,
Verhagen Okker,
Bartulos Monica,
MariscalPérez Natividad,
Collazo Carla,
GarciaBustillo Alvaro,
Calvo Sara,
Cubo Esther
Publication year - 2021
Publication title -
movement disorders clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 18
ISSN - 2330-1619
DOI - 10.1002/mdc3.13263
Subject(s) - wasting , bioelectrical impedance analysis , medicine , anthropometry , skeletal muscle , confounding , parkinson's disease , bayesian multivariate linear regression , physical therapy , disease , cross sectional study , body mass index , linear regression , pathology , machine learning , computer science
Background Skeletal muscle loss has been associated with declining physical performance and a negative prognostic effect on falls, disability, and mortality risk in Parkinson's disease. Objectives We aimed to analyze the clinical correlates associated with skeletal muscle wasting in Parkinson's disease. Methods This was a cross‐sectional, case–control, observational study. We collected information on dietary intake with a 24‐hour recall questionnaire, body composition with bioelectrical impedance, motor severity with the Unified Parkinson's disease Rating Scale, and physical activity with the Global Physical Activity Questionnaire. We used multivariate linear regression analysis to analyze the sociodemographic and clinical correlates associated with skeletal muscle loss after adjusting for confounding variables. Results Forty‐three patients with Parkinson's disease and 21 matched family members were included. Patients and family members had similar body composition, anthropometrics, and nutritional parameters. Advanced patients had similar nutrient intakes compared to patients with mild‐to‐moderate Parkinson's disease. In the multivariate linear regression analysis, female patients with low physical activity and low energy intake were more likely to have skeletal muscle loss. Conclusions Skeletal muscle wasting is a complex multifactorial problem. Dietary strategies and physical exercise should be recommended, especially to females with Parkinson's disease, to prevent significant skeletal muscle wasting.