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Phenomenology and Management of Subthalamic Stimulation‐Induced Dyskinesia in Patients With Isolated Dystonia
Author(s) -
Bledsoe Ian O.,
Dodenhoff Kristen A.,
San Luciano Marta,
Volz Monica M.,
Starr Philip A.,
Markun Leslie C.,
Ostrem Jill L.
Publication year - 2020
Publication title -
movement disorders clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 18
ISSN - 2330-1619
DOI - 10.1002/mdc3.12946
Subject(s) - dystonia , deep brain stimulation , dyskinesia , cervical dystonia , levodopa , medicine , subthalamic nucleus , neuroscience , physical medicine and rehabilitation , focal dystonia , parkinson's disease , psychology , anesthesia , disease
Background The pallidum has been the preferred DBS target for dystonia, but recent studies have shown equal or greater improvement in patients implanted in the STN. 1 Transient stimulation‐induced dyskinesia (SID) is frequently observed when stimulating this novel target, and there are no previously published video case reports of this phenomenon. Cases We describe in detail the SID phenomenology experienced by 4 patients who had been implanted with STN DBS for isolated dystonia. Conclusions SID can occur in focal, segmental, axial, or generalized distribution, can resemble levodopa‐induced dyskinesia choreiform or dystonic movements observed in Parkinson’s disease, and is generally transient and resolves with customized DBS programming. Providers should be aware that SID can occur after STN DBS when treating isolated dystonia and not assume movements are the result of worsening or spread of the underlying dystonia.

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