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Percutaneous Endoscopic Transgastric Jejunostomy ( PEG ‐J) Tube Placement for Levodopa‐Carbidopa Intrajejunal Gel Therapy in the Interventional Radiology Suite: A Long‐term Follow‐up
Author(s) -
Saddi Maria Valeria,
Sarchioto Marianna,
Serra Giulia,
Murgia Daniela,
Ricchi Valeria,
Melis Marta,
Arca Roberta,
Carreras Pierpaolo,
Sitzia Loredana,
Zedda Sandro,
Dui Giovanni,
Rossi Rosario,
Ticca Anna,
Melis Maurizio,
Cossu Giovanni
Publication year - 2018
Publication title -
movement disorders clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 18
ISSN - 2330-1619
DOI - 10.1002/mdc3.12569
Subject(s) - medicine , jejunostomy , percutaneous , carbidopa , neuroradiology , interventional radiology , adverse effect , percutaneous endoscopic gastrostomy , surgery , peg ratio , parkinson's disease , radiology , neurology , disease , levodopa , parenteral nutrition , finance , psychiatry , economics
Background Percutaneous endoscopic gastrojejunostomy ( PEG ) and radiologically inserted gastrojejunostomy ( RIG ) are both safe and effective techniques for gastrojejunal tube placement. The authors compared these 2 procedures in patients with advanced Parkinson's disease ( PD ) who required the continuous intrajejunal delivery of a levodopa/carbidopa gel suspension ( LCIG ). Methods Outcomes were retrospectively collated from 30 PEG and 12 RIG procedures performed at 2 centers in patients with advanced PD for the delivery of LCIG . Results Baseline clinical characteristics, incidence of early severe adverse events, late major complications, dropout, and the mean time‐lapse of tube replacements were comparable in the PEG and RIG groups. Conclusion The current results suggest that, in patients with PD , the RIG technique is as safe and effective as the endoscopic procedure, and it can be considered a valid option for patients who require LCIG when the endoscopic procedure is not available or unfeasible.