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Reversible Parkinsonism and Rapidly Progressive Dementia Due to Dural Arteriovenous Fistula: Case Series and Literature Review
Author(s) -
Lai Joshua,
Heran Manraj K.S.,
Stoessl A. Jon,
Gooderham Peter A.
Publication year - 2017
Publication title -
movement disorders clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 18
ISSN - 2330-1619
DOI - 10.1002/mdc3.12480
Subject(s) - parkinsonism , medicine , arteriovenous fistula , dementia , pathophysiology , surgery , tinnitus , pathology , audiology , disease
Background Dural arteriovenous fistula ( dAVF ) rarely presents with a syndrome of reversible parkinsonism and rapidly progressive dementia, which has been described in 19 patients to date. However, its presenting features, pathophysiology, and response to treatment have not been reviewed. Methods We report the clinical course and treatment of two novel patients with this syndrome. Results Despite severe presentations, both patients recovered fully after fistula obliteration. Conclusions Atypical parkinsonism with early cognitive changes and other focal neurological signs, along with features such as pulsatile tinnitus or worsening headache, should raise the possibility of dAVF . When treated, this syndrome is nearly always reversible, highlighting the importance of early diagnosis.