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Nocturia in Parkinson's Disease: Why Does It Occur and How to Manage?
Author(s) -
Batla Amit,
Phé Véronique,
De Min Lorenzo,
Panicker Jalesh N.
Publication year - 2016
Publication title -
movement disorders clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 18
ISSN - 2330-1619
DOI - 10.1002/mdc3.12374
Subject(s) - nocturia , medicine , desmopressin , overactive bladder , polyuria , disease , parkinson's disease , lower urinary tract symptoms , intensive care medicine , urinary system , urology , pediatrics , endocrinology , pathology , prostate , alternative medicine , cancer , diabetes mellitus
Background Nocturia is one of the commonest nonmotor symptoms in Parkinson's disease ( PD ) and has a significant impact on quality of life both for patients and their carers. There exists a relation between nocturia and poor sleep quality, falls, and institutionalization. Nocturia may manifest as a result of reduced functional bladder capacity or nocturnal polyuria; however, most often the cause is multifactorial. Disorders of circadian rhythm regulation are known to occur with sleep disturbances in PD may also contribute to nocturia. Methods and Results In this review, an overview of the assessment and management of nocturia in patients with PD is presented. History taking, medication review, and a bladder diary form the cornerstone of the evaluation. Urinalysis, ultrasonography, and urodynamic studies help to assess the cause for lower urinary tract symptoms and exclude concomitant pathologies, such as bladder outlet obstruction. Antimuscarinic medications are the first‐line treatment for the overactive bladder; however, caution is needed when using these medications in individuals predisposed to cognitive impairment. Desmopressin is effective for managing nocturnal polyuria. Conclusions An individualized approach is recommended to optimize the management of nocturia in PD .